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How does Epicure differ from other risk regression tools?

  • Provides a simple method for defining and fitting rate and risk regression models that go beyond the log linear models routinely available in most other packages. These include:
    • Excess relative rate and excess odds models for analyses dose response shape and effect modification
    • Excess risk/rate (risk/rate difference) models.
    • Additive and multiplicative joint effect models
  • Model specification is simple but powerful. It is easy to:
    • add or remove covariates from a model
    • fix the values of individual parameters at specific value
    • specify boundary constraints for individual parameters,
  • Powerful tools for the creation of detailed rate (person-year) tables
    • Multiple time scales (e.g., attained age, calendar time, smoking status and duration)
    • Time-dependent category variables (e.g., cumulative dose, pre-/post-menopause, number of pregnancies)
    • Multiple summary variables (e.g., multiple causes of death, current age/year/dose, pack years)
  • Either fully parametric or stratified rate (Poisson regression) or risk models (unconditional logistic regression)